What is Nattokinase?

June 22nd, 2009

Nattokinase was discovered in 1980, by Dr Hiroyuki Sumi, who was working at the Chicago University Medical School. He was testing 172 different foods for their ability to promote healthy circulation, and Nattokinase did the job better than any other substance he was testing.

Since then, additional research has been done on Nattokinase, including 17 published studies in Japan and here in the U.S. The results have been dramatic to say the least.

But to fully understand the significance of Nattokinase, you need to first understand “blood clotting”. Blood clotting is a normal and necessary process, it’s what stops the bleeding if you cut your finger for instance.

Our body produces compounds that make blood clots, one of the most important is called “Fibrin”. Fibrin is made up of sticky protein fibers which look like a tangled spider’s web.

Fibrin’s job is to stick to the blood vessel walls and act like a net, form a  lump or plug that stops the bleeding. Fibrin is also what determines the viscosity, or thickness of blood throughout our entire circulatory system.

Normal Fibrin levels will give you normal blood flow.

There is only one enzyme that breaks down Fibrin—an enzyme called “Plasmin”.

Remember, Fibrin is what’s forming a “web” that stops blood from flowing – so by breaking down Fibrin, Plasmin dramtically increases blood flow and thus brings down blood pressure.

Unfortunately, Plasmin production declines rapidly as we age.  If the drug companies could “bottle” Plasmin, they would have a staggering gold mine in their hands. They can’t. But Mother Nature can.

Nattokinase is “Mother Nature’s Plasmin” and works dramatically to support healthy circulation in two distinct ways.

First, Nattokinase is identical to Plasmin, so it can break down Fibrin!

Second, Nattokinase enhances your body’s natural production of Plasmin, further helping to break down the Fibrin.

In a nutshell, Nattokinase:

  • Supports normal circulation, blood flow and blood thickness
  • Supports your body’s normal blood-clotting mechanism
  • Supports your body’s production’s of Plasmin, which reduces Fibrin
  • Helps to maintain normal blood pressure levels

That’s why I call Nattokinase the “Roto Rooter” for your arteries.

Dr G.

Blood Pressure, Cholesterol, Clogged Arteries, Heart Health, Stroke , , , ,

  1. Curt
    September 4th, 2010 at 19:10 | #1

    Does Nattokinase stop your body from being able to clot?

  2. September 20th, 2010 at 14:42 | #2


    Thank you for your inquiry about the amazing Nattokinase substance.

    While it has profound declogging capacities as outlined in the newsletter, it is very high in Vitamin K-2 which is the coagulating compound utilized by the body for all clotting factors.

    This clotting action only occurs when the body signals that it requires it such as when a vein is slashed or for hemophiliac response.

    In fact the “K” given to the substance is the German word for coagulaton “Koagulaten”.

    I trust this answers your question.

  3. tamara
    August 16th, 2011 at 04:37 | #3

    I think this would be good for my mom,she is in a nurcing home.
    were do you get this or what is it made from? thank you for your time!

  4. August 16th, 2011 at 14:31 | #4

    Nattokinase is an extraordinary, natural compound that I feel everyone in the world should take each day for the giant benefits of naturally lowering blood pressure and declogging arteries to prevent stroke incidence.
    Nattokinase comes from fermented soybean cheese and is high in Vitamin K-2 which is needed for blood chemistry and needed for blood coagulation. It also acts like a “Key” to open the door to the bone and bone marrow “factory” to allow accumuted Calcium flow in, without high K-2 levels the Calcium accumulates with plaque and this can be a serious problem.

  5. Debby
    October 20th, 2011 at 07:14 | #5

    Doesn’t soybeans cause cancer? I have rheumotoid arthritis and have read that soybeans make your body think that it doesn’t have enough estrogen. Soybeans cause your body to make too much estrogen causing a overabundance of estrogen. Anything with soy anything in it, I, usually, avoid. But what about this? Fermented soybeans? I would like to hear your expertise on this. Thank you.

  6. August 18th, 2012 at 01:09 | #6

    Is it safe for a person who has Anti-Phospholipid Syndrome to take Natto products, e.g. Nattokinase, Menaquinone (MK7), etc., providing they do not take any other blood thinning medications?

  7. Kelly
    December 26th, 2012 at 01:14 | #7

    You say that nattokinase contains high levels of vitamin K2. Didn’t you mean that NATTO — the fermented food — contains K2? It’s my understanding that most nattokinase supplements have the K2 removed.

    Looking forward to your reply.

  8. Sally H.
    January 3rd, 2013 at 16:00 | #8

    Dear Dr. Garland, I was considering taking Fibrovran, for my large fibroid, as it’s main ingredient is Nattokinase. I have regular periods with no heavy bleeding, and no pain from my large 9cm fibroid. Is it safe for me to take Fibrovan, if it thins my blood? Please advise. Their website advertises that it will reduce the size of fibroids. I wonder if it will have any side effects. Please advise.
    Thanks, Sally

  9. Bobbie Z.
    April 27th, 2013 at 08:16 | #9

    Dr. Garland: I am hoping you will be able to give me some guidance regarding taking a Nattokinase supplement. Will Nattokinase supplements help those who suffer from capillaritis and is it safe to take if you have capillaritis?

    Also, the Nattokinase supplement I was researching, K2 has been removed. Is it safe to take a K2 supplement when taking Nattokinase or should one stop taking additional K2? Thanks for you help and advise.

  1. December 26th, 2008 at 17:35 | #1
  2. January 1st, 2009 at 16:22 | #2
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